What are the best weight-loss treatments?

The best treatment depends on the individual’s needs, price-range, and preferences. Some decrease appetite, while others change your body’s metabolism.

Generally, the most effective treatment available (as of 2026) is Zepbound; however, this option requires a weekly injection and is not covered by Medicaid or many insurance plans. On top of this, about half of patients report nausea.

Read what Dr. Connor says weight-loss treatments in the article on womansworld.com, Best Weight Loss Medications and Supplements: Your Expert-Ranked Guide for 2026. The article covers the pros and cons of four commonly prescribed weight-loss treatments so you can decide which may be right for you. If none of these options work for you, the article covers several over-the-counter weight-loss treatments to try.